Animal breeder cms11/29/2022 ![]() Half of their chromosomes are inherited from their mother and the other half from their father. This test will allow for you to make informed decisions with regards to future breeding plans.ĭomestic cattle have 60 chromosomes (58 autosomes and 2 sex chromosomes). Unistel Medical Laboratories can genetically test cattle for Pompe and CMS. It is therefore important to know the status of all animals to be used for breeding purposes. However, when mated to a carrier female there is a 25 % chance for the offspring to be affected, 50 % of the offspring can be carriers and a 25 % chance for normal offspring. Carrier animals appear normal and can perform as well as non-carriers. The average life of calves that are affected with Pompe and CMS is less than 12 months and should be culled.Ĭalves with only one copy of these recessive disorders and one copy of the normal gene appear normal and are known as carriers. Pompe and CMS are autosomal recessively inherited genetic disorders where carriers of the disorders cannot be phenotypically distinguished. This weakness is caused by defective nerve-muscle interaction. A defect in the function of this enzyme causes a build-up of glycogen leading to muscle weakness throughout the body including the heart.Ĭongenital Myasthenia Syndrome (CMS) is an auto-immune disorder found mainly in red Brahman cattle and is characterized by varying degrees of progressive general muscle weakness. The conversion of glycogen to glucose is catalyses by the enzyme acid alpha-glycosidase. Pompe disease is a glycogen storage disorder confined to grey Brahman cattle. ![]()
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